DRESS Syndrome: A Case Report

Gözdem Kaykı 1, Yasemin Özsürekçi 2, Elif Arslanoğlu 1, Mustafa Şenol Akın 1, Cansın Saçkesen 3, Diclehan Orhan 4, Ateş Kara 2
1Hacettepe Üniversitesi Tıp Fakültesi, Çocuk Sağlığı ve Hastalıkları Bilim Dalı, Ankara, Türkiye
2Hacettepe Üniversitesi Tıp Fakültesi, Çocuk Enfeksiyon Hastalıkları Bilim Dalı, Ankara, Türkiye
3Hacettepe Üniversitesi Tıp Fakültesi, Çocuk Alerji Bilim Dalı, Ankara, Türkiye

J Pediatr Inf 2016; 10: 99-103
DOI: 10.5152/ced.2015.1768
Key Words: DRESS syndrome, eosinophilia, drug hypersensitivity

A 5-year-old female patient, who had growth and mental retardation and epilepsy and who used valproic acid for 2 years, presented with fever and red maculopapular rash over her entire body. Eosinophilia and elevated liver function test were observed on blood examination. According to the clinical and laboratory findings, she was diagnosed with “drug rash with eosinophilia and systemic symptoms” (DRESS) syndrome. Our case indicates that when evaluating a child with fever and rash, particularly a child with a history of antiepileptic drug use, DRESS syndrome should be considered in the differential diagnosis.(J Pediatr Inf 2016; 10: 99-103)